Prostate Cancer Treatment in Pune by Dr. Mohamad Ali

Understanding Prostate Cancer

Prostate cancer is a condition in which malignant cells develop in the tissues of the prostate gland in males. The prostate is a small, walnut-sized gland located just below the bladder and in front of the rectum. It surrounds the urethra, the tube responsible for carrying urine from the bladder out of the body, and produces fluid that forms part of semen.

Prostate cancer commonly develops slowly, especially in older men, and may remain confined to the prostate for many years. When identified early, treatment outcomes are generally favorable. Advancements in diagnostic imaging and minimally invasive surgery have significantly improved Prostate cancer treatment in Pune, allowing for accurate diagnosis and structured treatment planning.

Signs and Symptoms

Prostate cancer is most frequently seen in men above the age of 50. In its early stages, symptoms may be mild or absent, which is why regular screening is important.

Common symptoms may include:

• Weak or reduced urine flow
• Frequent urination, especially at night
• Difficulty starting or stopping urine flow
• A sudden urge to urinate
• Incomplete emptying of the bladder
• Burning sensation during urination
• Blood in urine or semen
• Persistent pain in the lower back, hips, or pelvis
• Fatigue, dizziness, or pale skin due to anemia

These symptoms may also be associated with non-cancerous prostate conditions, but evaluation is essential to rule out malignancy.

Diagnosis of Prostate Cancer

Diagnosis involves a combination of clinical examination and imaging studies. Common diagnostic methods include:

Clinical Evaluation

Detailed medical history and physical examination

Digital Rectal Examination (DRE) to assess prostate size and texture

Laboratory and Imaging Tests

Prostate-Specific Antigen (PSA) blood test

Multiparametric MRI of the pelvis

Transrectal ultrasound, often used during biopsy

MRI-targeted or systematic prostate biopsy

PSMA scan and PET-CT for advanced or metastatic disease

A biopsy confirms the diagnosis and determines the Gleason score, which indicates cancer aggressiveness.

Factors Affecting Treatment Planning

The choice of treatment depends on several factors, including:

• Cancer stage and PSA level
• Gleason score and Grade Group
• Extent of cancer spread
• Patient’s age and overall health
• Previous treatments and patient preferences

Personalized planning plays an important role in Prostate cancer treatment options Pune, ensuring treatment decisions are aligned with disease severity and patient needs.

Treatment Options for Prostate Cancer

Active Surveillance

Used for low-risk or slow-growing cancers, especially in older patients with limited symptoms.

Surgical Treatment

Surgery involves removal of the prostate gland and, in some cases, nearby lymph nodes. Surgical approaches include:

• Radical prostatectomy

• Robotic-assisted or laparoscopic prostatectomy

• Transurethral resection of the prostate (TURP) for symptom relief

• Robotic surgery allows precise removal of cancer while supporting preservation of urinary control.

Radiation and Radiopharmaceutical Therapy

High-energy radiation targets cancer cells to stop their growth.

Hormone Therapy

Androgen deprivation therapy (ADT) reduces hormone levels that promote cancer growth.

Systemic Therapies

• Chemotherapy
• Targeted therapy
• Immunotherapy
• Bisphosphonate therapy for bone metastases
• These therapies are selected based on disease stage and progression.

Recovery and Follow-Up Care

Recovery after treatment varies depending on the chosen approach. Patients undergoing robotic surgery usually resume routine activities within a few weeks. Regular PSA monitoring and follow-up evaluations are essential to track recovery and long-term outcomes. With structured care and monitoring, Prostate cancer treatment in Pune supports both disease control and quality of life.